DNA Discovery Sheds Light on Bladder Cancer

Scientists have been studying cancer for decades. While there’s a lot we’ve learned, there’s also a lot that we still don’t know about cancer. Thanks to DNA technology, scientists are continuing to learn clues about the cancer process and mutations–with the hope of refining cancer treatment.

A study published in Science is the first of its kind. The study analyzes the DNA changes of healthy and diseased human bladder tissue to better understand the genetic changes in healthy and diseased bladder tissue. The results revealed “cancer-driving” mutations are common in healthy bladder tissue.

Surprisingly, the research team found high variability in the number and types of cancer mutations, as well as in the mutation frequency between individuals. This suggests a wide range of factors influence the cancer mutations in the bladder.

Tobacco use has long been a risk factor in bladder cancer. Though the bladder does not come into direct contact with tobacco, the chemicals are filtered out of the body by the kidneys. Therefore, the bladder comes in contact with tobacco in the urine. The study revealed a new mutational signature associated with smoking, confirming the smoking theory.

Thomas Mitchell, a senior author of the study, said: “Like many cancers,  of bladder cancer gives the patient a much greater chance of survival. The presence of mutations in key cancer genes in bladder tumors that are usually absent in normal tissue opens up the possibility of looking for these changes in fragments of DNA that are present in urine. These ‘liquid biopsies’ could be a non-invasive way to screen for bladder cancer earlier, which could help reduce the number of people who die from this disease.”

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The Results of Ancient DNA

Analyzing ancient DNA has led to some magnificent findings over the years. We’ve learned a great deal about the history of the world through gene analytics. Now, scientists are discovering the immigration patterns of eastern humankind.

The Eastern Eurasia regions contain approximately 2.3 billion people today. That’s 30% of the world’s population! Archaeologists have learned from fossils and artifacts that humans have occupied Southeast Asia for 60,000 years and East Asia for 40,000 years.

Using bones, fossils, and seeds used by ancient farmers, scientists tracked the migration patterns of the Eurasia peoples.

A particularly interesting discovery is that while many Asian peoples look similar, Eurasian people most likely looked distinct. The genetic codes showed a vast diversity in gene pools, meaning that Eurasian people probably didn’t look the way they do today. It’s likely that their variety of genes were expressed in many ways.

Other genetic patterns indicate connections between individuals from ancient Tibetans, Mongolia, and northern China. However, research concludes that DNA common to all present-day East Asians became consistent about 9,000 years ago.

While this discovery may not impact the lay-person (besides updating your ancestry map!), it shows the rapidly-advancing technology that continues to be helpful both for archaeology and present circumstances.

DNA Paternity Testing provides rock-solid answers to important questions like parentage and ancestry. With over 2,000 centers nationwide, DNA Paternity Testing Centers is one of the largest, most affordable, networks of accredited DNA testing labs in the United States. Our price is unbeatable without sacrificing quality. We offer DNA testing for paternity, maternity and all other relationships (grandparents, siblings, aunts/uncles).

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Can DNA Tests Predict Your Perfect Diet?

DNA testing is becoming increasingly more advanced with every passing year. The scientific community has jumped from using DNA to confirm basic family relations or assisting in forensics to now–predicting the perfect diet that will help you lose weight.

But does it actually work?

The basic science behind DNA diet kits is that specific genes influence how the individual processes food. For instance, someone who has the type CC of the APOC3 gene might be advised to follow a lower-fat diet. That’s because the type CC variation influences triglyceride processing, which can elevate levels of LDL cholesterol when following higher-fat diets.

However, studies show that 110 pairs of identical twins had varying metabolic responses to food depending on meal content, meal context, body composition, and metabolites found in the body’s cells.

In fact, these DNA diet tests aren’t more helpful than traditional advice — limit carbs, increase fiber, cut sodium, and the like. The U.S. Department of Health and Human Services shows that genetics only make up 10% of someone’s overall health. Contrastly, behaviors, social and economic factors together make up 70% of overall health.

This is not to say that genetics has no factor in health. Certain diseases, such as Type I diabetes, is known to be affected by genes. However, if you’re looking to improve your overall health and lose weight, it’s more beneficial to focus on lifestyle changes rather than the genetic component.

DNA Paternity Testing provides rock-solid answers to important questions like parentage and ancestry. With over 2,000 centers nationwide, DNA Paternity Testing Centers is one of the largest, most affordable, networks of accredited DNA testing labs in the United States. Our price is unbeatable without sacrificing quality. We offer DNA testing for paternity, maternity and all other relationships (grandparents, siblings, aunts/uncles).

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DTC Looking to Partner With Healthcare Industry

Direct-to-consumer (DTC) tests such as Ancestry.com and 23andMe skyrocketed in sales during the mid-2010’s. DNA kits were all the rage for almost every holiday and birthday. However, in the past few years, this has significantly tapered off.

This could be due to several reasons:

  • After receiving their results, most people aren’t inclined to purchase another DTC test. Since so many Americans have already had a DNA test, there are only so many consumers left to test.
  • Americans may be concerned over DNA information security and are waiting until laws ensure the privacy of such information.
  • Besides for the sake of sheer curiosity, knowing your genetic history has little impact on your daily life.

DTC companies have been scrambling to find new ways to coax consumers to either take the plunge of a first-time purchase or put a new spin on the product to entice a repeat-purchase.

However, now DTC may have found an alternative: partnering with the healthcare system. Seemingly, this would benefit both parties. The DTC wouldn’t have to close their doors, and physicians could enhance their healthcare with the genetic information derived from DNA tests.

This might be well and good for DTC, but DNA Paternity Testing is already incorporated into the healthcare industry! That means there won’t be any kinks or lost information. Our tests can be ordered by physicians or self-ordered.

DNA Paternity Testing provides rock-solid answers to important questions like parentage and ancestry. With over 2,000 centers nationwide, DNA Paternity Testing Centers is one of the largest, most affordable, networks of accredited DNA testing labs in the United States. Our price is unbeatable without sacrificing quality. We offer DNA testing for paternity, maternity and all other relationships (grandparents, siblings, aunts/uncles).

Call us today at 866.944.9546 or ORDER ONLINE!

Brother and Sister Reunited with DNA Test

Sally Laurent was like many people when COVID-19 struck: there were people she still wanted to meet!

Laurent and her older half-sister were both adopted as babies. They were both raised Jewish in their Long Island home, but Laurent always wondered about her biological family. Knowing that it may be now or never, Laurent took a DNA test.

“I discovered there was not one bit of Jewish blood in me, which is okay because I’ve benefited from all of this, you know,” she said.

But more important than her lack of Jewish heritage was that she had a brother–and he also lived on Long Island!

Although Bob Stanco knew he was one of five children, he wasn’t aware of Laurent’s existence. Laurent is the sister he never knew he had.

“I knew I had and brother and a sister, full-blooded, who lived with me growing up. Prior to that, I had no idea anyone until my parents passed away,” Stanco said.

Laurent and Stanco are eager to meet once the pandemic is over. But in the meantime, they are making up for the lost time and getting to know one another through phone calls.

You can watch the heartwarming story in the video below:

DNA Paternity Testing provides rock-solid answers to important questions like parentage and ancestry. With over 2,000 centers nationwide, DNA Paternity Testing Centers is one of the largest, most affordable, networks of accredited DNA testing labs in the United States. Our price is unbeatable without sacrificing quality. We offer DNA testing for paternity, maternity and all other relationships (grandparents, siblings, aunts/uncles). Call us today at 866.944.9546 or ORDER ONLINE!

Smallpox Virus Found in DNA of Vikings

For a long time, geneticists, archaeologists, and scientists have studied the genetic makeup of historical findings. Most recently, bones and teeth of several people who lived in northern Europe during the Viking age are being studied by a team at the University of Cambridge. The reason: the bones and teeth carry a strain of ancient smallpox viruses.

The Variola virus has been around for millennia, plaguing populations as old as the Egyptians. This is the virus Barbara Mühlemann and her colleagues have traced and are studying. Their findings are pushing the boundaries on what scientists understand about virus evolution.

The group has thus far determined that the ancient smallpox strain was “derived from the same ancestor as the 20th-century virus, but didn’t give rise to it. Instead, they are a now-extinct side branch.” However, this goes against conventional virology theories, which state that  viruses are most deadly when they first jump to humans and evolve to become less deadly,

Antonio Alcamí at the Autonomous University of Madrid, Spain, hypothesizes that the Viking-age virus wasn’t as deadly as the 20th-century virus. Another explanation given by the team was that the smallpox virus jumped from animals to people more than once.

Learn more about Mühlemann’s work in this video:

DNA Paternity Testing provides rock-solid answers to important questions like parentage and ancestry. With over 2,000 centers nationwide, DNA Paternity Testing Centers is one of the largest, most affordable, networks of accredited DNA testing labs in the United States. Our price is unbeatable without sacrificing quality. We offer DNA testing for paternity, maternity and all other relationships (grandparents, siblings, aunts/uncles).

Call us today at 866.944.9546 or ORDER ONLINE!

GEDmatch Announces Security Breach

Many concerns have been raised over the security of stored DNA information. Consumers want to know who has access to their genetic information and under what circumstances, whether their information is sold, and to whom, and what laws protect their genetic information. The following video gives an overview of current laws in place to protect genetic information:

There isn’t much assurance or explanation of privacy given by direct-to-consumer companies. Even worse, GEDmatch confirmed they had two security breaches in July.

GEDmatch changed its privacy policy, allowing users to opt-in to their DNA being used for police searches. However, users reported that their settings had been changed without their permission; all profiles could be searched by police.

GEDmatch took the site down to fix the security breach but is now up and running again. However, this is not the first time a direct-to-consumer company has been hacked, and it won’t be the last. Dare you trust a direct-to-consumer company with your personal genetic information?

With DNA Paternity Testing, we use extreme measures to keep your medical information secure. We train all our staff on all HIPAA compliance policies and ensuring that all tests and counseling remain confidential.  We never sell or release your information except if needed to comply with HIPAA standards. Your results are safe with us!

DNA Paternity Testing provides rock-solid answers to important questions like parentage and ancestry. With over 2,000 centers nationwide, DNA Paternity Testing Centers is one of the largest, most affordable, networks of accredited DNA testing labs in the United States. Our price is unbeatable without sacrificing quality. We offer DNA testing for paternity, maternity and all other relationships (grandparents, siblings, aunts/uncles).

Call us today at 866.944.9546 or ORDER ONLINE!

Emerging Technology to Secure DNA

It’s a growing problem: the security of our DNA information. Who has access to it, and under what circumstances? Is your information sold? Can you have your information deleted? What will happen to your information in the future? Watch this video to learn more about poor security of DNA tests:

As the years have gone on, more people have become wary of the security measures used to protect their DNA and the scams associated with mailing their collected DNA. Direct-to-consumer test companies like Ancestry.com and 23andMe have especially felt the effects of consumer uneasiness through declining sales.

But engineers at Duke University have developed at DNA “barcoding” system that ensures swabbed DNA material is not swapped or tampered with on the way to the laboratory. While this doesn’t affect how information is stored and accessed, it is a step in the right direction towards better DNA security.

But with DNA Paternity Testing, we use extreme measures to keep your medical information secure. We train all our staff on all HIPAA compliance policies and ensuring that all tests and counseling remain confidential.  We never sell or release your information except if needed to comply with HIPAA standards. Your results are safe with us!

DNA Paternity Testing provides rock-solid answers to important questions like parentage and ancestry. With over 2,000 centers nationwide, DNA Paternity Testing Centers is one of the largest, most affordable, networks of accredited DNA testing labs in the United States. Our price is unbeatable without sacrificing quality. We offer DNA testing for paternity, maternity and all other relationships (grandparents, siblings, aunts/uncles).

Call us today at 866.944.9546 or ORDER ONLINE!

Korean Adoptee Uses DNA to Demand Paternity Information

Kara Bos has been on a search for three years to find her biological family.

Kara was abandoned at two years old in Goesan, South Korea. Adopted at three years old in 1984 by loving parents, Kara was mostly disinterested in finding her birth family. But when Kara became a mother and her daughter approached the same age as when she was abandoned, Kara couldn’t understand why her mother would give her up. Kara began an intense search to find her parents.

Kara researched adoptee forums on Facebook, adoptee rights organizations, and online genealogy platforms. She took DNA tests through Family Tree DNA, then uploaded the results to MyHeritage. Then the waiting began.

A few years later, Kara learned she had been matched with a relative—her nephew, or the grandson of her biological father. However, Kara was met with resistance to reaching her father by her nephew’s mother and aunts (her presumed half-sisters), and Kara filed a lawsuit which resulted in a court-ordered paternity test.

Kara briefly met her father on his apartment doorstep, who brushed her aside and has had no further contact. The DNA test did confirm, however, that he was Kara’s biological father.

The lawsuit, if ruled in favor of Kara, would reward Kara with legal recognition as her Korean father’s daughter, officially being entered into his family registry. It’s the first of its kind, and could set a new precedent for information gained from DNA tests.

DNA Paternity Testing provides rock-solid answers to important questions like parentage and ancestry. With over 2,000 centers nationwide, DNA Paternity Testing Centers is one of the largest, most affordable, networks of accredited DNA testing labs in the United States. Our price is unbeatable without sacrificing quality. We offer DNA testing for paternity, maternity and all other relationships (grandparents, siblings, aunts/uncles).

Call us today at 866.944.9546 or ORDER ONLINE!

Siblings Reunited After 50 Years

Irish siblings Helen Ward and David McBride didn’t know they were siblings—even though they had the same parents.

In 1962, David was found in a tartan bag in a car on the outskirts of Belfast city. In 1968 Helen was abandoned and found, also in a tartan bag, on the other side of the Irish border, in Dundalk.

David and Helen have spent their lives searching for biological family, and that’s where DNA testing came in. They both took DNA tests and uploaded them to the database, hoping to find blood relatives. They were reunited on the television show Long Lost Family: Born without a Trace and learned their parents’ story.

Their father was a married Protestant with 14 other children. He had an affair with their mother—a Catholic woman 17 years his junior—that lasted over 40 years. The sectarian conflict in Northern Ireland would have denounced their relationship as a scandal, and it is for this reason David and Helen believe their mother gave them up as infants.

Their father passed away in Dublin in 1993, and their passed away in 2017.

Despite never meeting their parents, David and Helen have a positive outlook on their new family. “We started one journey,” said David. “Now we are on another, getting to know each other and our family.”

DNA Paternity Testing provides rock-solid answers to important questions like parentage and ancestry. With over 2,000 centers nationwide, DNA Paternity Testing Centers is one of the largest, most affordable, networks of accredited DNA testing labs in the United States. Our price is unbeatable without sacrificing quality. We offer DNA testing for paternity, maternity and all other relationships (grandparents, siblings, aunts/uncles). Call us today at 866.944.9546 or ORDER ONLINE!